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Ionis announces changes to Board of Directors

MWN-AI** Summary

Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) has announced significant changes to its Board of Directors, effective June 4, 2026. B. Lynne Parshall, who has been a director since September 2000 and a key figure in various executive roles, including Chief Operating Officer and Chief Financial Officer, will retire. Parshall's tenure with Ionis began in 1991, during which she has made numerous contributions to the company. Joseph Wender, another long-standing director since January 1994 and the lead independent director since 2020, will also be stepping down. Known for his influential role at Goldman Sachs, Wender has been recognized with the Ionis Career Achievement Award for his significant impact.

The board will welcome Peter N. Reikes back as a director. Reikes has extensive experience in healthcare investment banking and held senior strategic roles, most recently as a senior strategy advisor with the Advanced Research Projects Agency for Health (ARPA-H). His prior experience includes serving as a senior advisor at the FDA and as vice chairman at Stifel, Nicolaus & Company. Reikes previously served on the Ionis Board from 2018 to 2021 before he joined the FDA.

Chairman Joseph Loscalzo and CEO Brett P. Monia expressed gratitude for the contributions of Parshall and Wender, emphasizing their pivotal roles in shaping Ionis as a leader in biotech. Monia expressed enthusiasm for Reikes's return, noting his blend of financial insights and industry expertise will be valuable as Ionis navigates its growth and innovation in RNA-targeted therapies. The company, a pioneer in this field, remains committed to improving the lives of patients with serious diseases through its advanced pipeline and ongoing research.

MWN-AI** Analysis

Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) recently announced significant changes to its Board of Directors, marking an important transition that could impact investor sentiment and market perception. The retirements of B. Lynne Parshall and Joseph Wender, stalwarts of the board since the early '90s, signal the end of an era for Ionis. Their lengthy tenures have provided invaluable leadership and insight during critical phases of the company. This leadership transition may create uncertainty among investors accustomed to their steady stewardship, especially given the competitive nature of the biotech industry.

In contrast, the reappointment of Peter N. Reikes as a director could prove to be a strategic move, enhancing the board's capabilities. Reikes’s extensive background in healthcare investment banking and regulatory affairs, particularly his recent role at the FDA, positions him as a key asset for Ionis. His experience in financing and advising biotech firms could bolster the company’s strategy, especially as it navigates through a period of rapid growth and an evolving pipeline.

Investors should consider this board transition as a critical juncture for Ionis. The potential for new ideas and strategies brought by Reikes might even outweigh the loss of the longstanding directors. However, vigilance is necessary. Investors should monitor how this change influences Ionis’s strategic direction, particularly regarding its innovative RNA-targeted therapies and pipeline advancements.

In summary, while there could be initial volatility due to the leadership changes, the addition of a seasoned director like Reikes potentially positions Ionis well for future growth. Current shareholders should maintain a close watch on upcoming announcements and performance indicators, while prospective investors may find this an opportune moment to assess Ionis, given its groundwork in pioneering biotechnology.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: Business Wire

– Lynne Parshall and Joseph Wender to retire at end of term in June 2026 and Peter Reikes to join Ionis Board –

Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced upcoming transitions on its Board of Directors. B. Lynne Parshall, Esq., and Joseph Wender will be retiring at the end of their term and Peter N. Reikes will be rejoining as a director. The changes will be effective June 4, 2026.

Ms. Parshall has served as a director since September 2000. Previously, she served as Ionis’ chief operating officer from December 2007 through December 2017 and as chief financial officer from June 1994 through December 2012. Ms. Parshall joined Ionis in 1991 and served in various executive roles during her tenure. Mr. Wender has served as a director since January 1994. Mr. Wender joined Goldman, Sachs & Co. in 1971 and became a general partner of that firm in 1982, where he headed the Financial Institutions Group for over a decade. Since January 2008, he has been a senior consultant to Goldman Sachs & Co. Mr. Wender has served as Ionis’ lead independent director since 2020. Both Ms. Parshall and Mr. Wender are recipients of the Ionis Career Achievement Award, which recognizes individuals who have made the most significant contributions to the company.

“We thank Lynne and Joe for their distinguished contributions throughout their long tenures – they have both provided valued, expert counsel throughout every significant moment in Ionis’ journey over the last three decades,” said Joseph Loscalzo, M.D., Ph.D., chairman, Ionis Board of Directors. “I also want to welcome Peter back to the Board. His unique combination of financial and industry experience will be critical as the company continues through a period of rapid growth and pipeline progress.”

Most recently, Peter Reikes was senior strategy advisor with the Advanced Research Projects Agency for Health (ARPA-H) from December 2024 to February 2026, which he joined after serving for over three years as senior advisor to the U.S. Food and Drug Administration (FDA). Prior to that, he served as a vice chairman in the Investment Banking Division at Stifel, Nicolaus & Company, Incorporated. Prior to joining Stifel in 2010, Mr. Reikes spent eleven years at Cowen and Company, LLC, where he was vice chairman and head of Healthcare Investment Banking, and over fourteen years at PaineWebber Incorporated, where he was a managing director and head of Healthcare Investment Banking. Over the course of his career, Mr. Reikes has been a director of numerous biotechnology companies and other healthcare-related organizations. Mr. Reikes received his B.A. in Economics from the University of California at Los Angeles and his M.B.A. in Finance from The Wharton School at the University of Pennsylvania. He previously served as an Ionis director from 2018-2021 and stepped down when he joined the FDA as senior advisor.

“I am grateful to Lynne and Joe for their wisdom, insight and friendship throughout the years – they have played a critical role in helping to shape the innovative, fully integrated and highly successful biotech company that Ionis is today,” said Brett P. Monia, Ph.D., chief executive officer, Ionis. “I am thrilled to have Peter rejoin the board as he has worked with so many innovative companies in various stages of development and we welcome his broad financial, industry and regulatory expertise.”

About Ionis Pharmaceuticals, Inc.

For three decades, Ionis has invented medicines that bring better futures to people with serious diseases. Ionis currently has marketed medicines and a leading pipeline in neurology, cardiometabolic disease and select areas of high patient need. As the pioneer in RNA-targeted medicines, Ionis continues to drive innovation in RNA therapies in addition to advancing new approaches in gene editing. A deep understanding of disease biology and industry-leading technology propels our work, coupled with a passion and urgency to deliver life-changing advances for patients. To learn more about Ionis, visit Ionis.com and follow us on X (Twitter) , LinkedIn and Instagram .

Ionis Forward-looking Statements

This press release includes forward-looking statements regarding Ionis' business, the therapeutic and commercial potential of our commercial medicines, additional medicines in development and technologies, and our expectations regarding development and regulatory milestones. Any statement describing Ionis' goals, expectations, financial or other projections, intentions or beliefs is a forward-looking statement and should be considered an at-risk statement. Such statements are subject to certain risks and uncertainties including those inherent in the process of discovering, developing and commercializing medicines that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such medicines. Ionis' forward-looking statements also involve assumptions that, if they never materialize or prove correct, could cause its results to differ materially from those expressed or implied by such forward-looking statements. Although Ionis' forward-looking statements reflect the good faith judgment of its management, these statements are based only on facts and factors currently known by Ionis. Except as required by law, we undertake no obligation to update any forward-looking statements for any reason. As a result, you are cautioned not to rely on these forward-looking statements. These and other risks concerning Ionis' programs are described in additional detail in Ionis' annual report on Form 10-K for the year ended December 31, 2025, and most recent Form 10-Q, which are on file with the Securities and Exchange Commission. Copies of these and other documents are available from the Company. In this press release, unless the context requires otherwise, "Ionis," "Company," "we," "our" and "us" all refer to Ionis Pharmaceuticals and its subsidiaries.

Ionis Pharmaceuticals ® is a trademark of Ionis Pharmaceuticals, Inc.

View source version on businesswire.com: https://www.businesswire.com/news/home/20260309350880/en/

Ionis Investor Contact:
D. Wade Walke, Ph.D.
IR@ionis.com 760-603-2331

Ionis Media Contact:
Hayley Soffer
media@ionis.com 760-603-4679

FAQ**

How might the retirement of B. Lynne Parshall and Joseph Wender impact the strategic direction of Ionis Pharmaceuticals Inc. IONS, given their long tenures and contributions to the company?

The retirement of B. Lynne Parshall and Joseph Wender could lead to a significant shift in Ionis Pharmaceuticals' strategic direction, as their extensive experience and insights have been foundational to the company's growth and innovation in the biotech sector.

What expertise does Peter N. Reikes bring to Ionis Pharmaceuticals Inc. IONS that could influence its growth and pipeline development moving forward?

Peter N. Reikes brings extensive experience in corporate strategy, finance, and capital markets, which can significantly influence Ionis Pharmaceuticals Inc.'s growth and pipeline development through effective resource allocation and strategic partnerships.

How will the upcoming leadership transitions influence investor confidence in Ionis Pharmaceuticals Inc. IONS, particularly regarding its product pipeline and market position?

The upcoming leadership transitions at Ionis Pharmaceuticals Inc. could create uncertainty that may temporarily dampen investor confidence, but if new leaders effectively communicate strategic plans for its product pipeline and market position, it could bolster long-term optimism.

What specific challenges does Ionis Pharmaceuticals Inc. IONS anticipate as it moves into this new phase of leadership with the board changes taking effect in June 2026?

Ionis Pharmaceuticals Inc. anticipates challenges related to strategic alignment, potential shifts in corporate culture, stakeholder expectations, and investor confidence as it navigates leadership transitions amid an evolving competitive landscape in the biotech sector.

**MWN-AI FAQ is based on asking OpenAI questions about Ionis Pharmaceuticals Inc. (NASDAQ: IONS).

Ionis Pharmaceuticals Inc.

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