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Monopar Announces ALXN1840 Data Selected for Late-Breaker Presentation at EASL Congress 2025

MWN-AI** Summary

On April 29, 2025, Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage biopharmaceutical firm, announced that data regarding its drug candidate ALXN1840 (tiomolybdate choline) has been accepted for a late-breaker presentation at the European Association for the Study of the Liver (EASL) International Liver Congress 2025. The congress, taking place from May 7 to May 10 in Amsterdam, is a leading event in the hepatology field, where new and impactful research is showcased.

The late-breaker session is particularly prestigious, reserved for the most significant and current findings that have the potential to influence the field profoundly. Monopar's acceptance for this category reflects the importance of the research, which focuses on the long-term efficacy and safety of ALXN1840 in patients suffering from Wilson disease, a genetic disorder that leads to excessive copper accumulation in the body.

The poster presentation titled "Sustained long-term clinical improvement in Wilson disease patients on tiomolybdate choline" will be presented by Dr. Karl Heinz Weiss on May 7 at 8:30 a.m. CET, further enhancing the visibility of Monopar's innovative approach to treating this condition. The abstract number for the presentation is LB25251, and attendees can expect to see compelling evidence of the drug's benefits.

Monopar Therapeutics also has a diverse pipeline that includes late-stage programs and other investigational therapies for advanced cancers, positioning the company as a significant player in the biotechnology landscape. Interested parties can access the poster online at Monopar's website on the day of the presentation.

MWN-AI** Analysis

Monopar Therapeutics Inc. (Nasdaq: MNPR) recently announced its ALXN1840 (tiomolybdate choline) will be showcased in a late-breaker poster presentation at the prestigious EASL International Liver Congress 2025. This marks a significant event for the company, as late-breaker presentations are typically reserved for groundbreaking research with potential substantial impact, indicating the underlying strength and relevance of the ALXN1840 data.

The focus on the long-term efficacy and safety of ALXN1840 for Wilson disease comes at a crucial time for Monopar, as the company seeks to solidify its position in the competitive biopharmaceutical market. Wilson disease, a rare genetic disorder that leads to excessive copper accumulation in the body, presents an unmet medical need for effective treatments. Given that late-breaking presentations are competitive and rigorously reviewed, the accepted data could potentially drive investor confidence.

Investors should closely monitor the presentation scheduled for May 7, where Dr. Karl Heinz Weiss will present findings expected to shed light on sustained clinical improvement for patients. Positive outcomes could catalyze a favorable response in stock price, particularly if the data illustrate a clear advantage over existing treatment options.

Additionally, Monopar's diversified drug pipeline—ranging from ALXN1840 to its radiopharma programs targeting advanced cancers—suggests potential for growth beyond Wilson disease. As with all biotech investments, the volatility can be substantial surrounding data releases and clinical trial results.

In summary, it would benefit investors to stay informed on the outcomes from EASL, assess the market reactions, and keep an eye on Monopar’s broader development trajectory. Given the inherent risks, a balanced approach with a watchful eye on both upcoming news and the company’s long-term pipeline strategy is advisable.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: GlobeNewswire

WILMETTE, Ill., April 29, 2025 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage biopharmaceutical company focused on developing innovative treatments for patients with unmet medical needs, today announced that data on the long term efficacy and safety of its ALXN1840 (tiomolybdate choline) drug candidate for Wilson disease has been accepted for a late-breaker poster presentation at the European Association for the Study of the Liver (“EASL”) International Liver Congress 2025. EASL is recognized as one of the premier events in the hepatology space and will be held in Amsterdam, Netherlands from May 7 – 10, 2025.

Late-breaker provides an opportunity to present “the most recent and significant findings,” according to EASL. Criteria for late-breaker abstracts include: (1) they present the latest, up-to-date research findings; (2) the research is considered highly significant with the potential to impact the field in a substantial manner; and (3) clinical studies should be prospective. Late-breaker abstracts undergo a rigorous review, and the acceptance rate is lower than regular abstracts with only the most compelling abstracts selected.

Details of the EASL Congress 2025 late-breaker poster presentation are as follows:

Title: Sustained long-term clinical improvement in Wilson disease patients on tiomolybdate choline
Abstract Number: LB25251
Session: Late-breaker Posters
Date and Time: Wednesday, May 7, 8:30 a.m. CET
Presenter: Karl Heinz Weiss, M.D.
Location: Amsterdam, Netherlands

The poster to be presented at EASL 2025 will be available online at www.monopartx.com on May 7, 2025.

About Monopar Therapeutics Inc.

Monopar Therapeutics is a clinical-stage biotechnology company with late-stage ALXN1840 for Wilson disease, and radiopharma programs including Phase 1-stage MNPR-101-Zr for imaging advanced cancers, and Phase 1a-stage MNPR-101-Lu and late preclinical-stage MNPR-101-Ac225 for the treatment of advanced cancers. For more information, visit: www.monopartx.com.

CONTACT:

Monopar Therapeutics Inc.
Investor Relations
Quan Vu
Chief Financial Officer
vu@monopartx.com

Follow Monopar on social media for updates:

X: @MonoparTx LinkedIn: Monopar Therapeutics


FAQ**

What key findings related to the efficacy and safety of Monopar Therapeutics Inc. MNPR's ALXN1840 will be highlighted in the late-breaker presentation at EASL 2025, and how could this impact the market for Wilson disease treatments?

The late-breaker presentation at EASL 2025 will showcase promising efficacy and safety data for Monopar Therapeutics Inc.'s ALXN1840, potentially positioning it as a leading treatment option for Wilson disease and significantly impacting market dynamics and patient outcomes.

How do the results of the long-term study on ALXN1840 presented by Monopar Therapeutics Inc. MNPR compare to existing treatments for Wilson disease in terms of efficacy and safety?

The long-term study results of ALXN1840 by Monopar Therapeutics Inc. suggest improved efficacy and a favorable safety profile compared to existing Wilson disease treatments, positioning it as a promising alternative; however, comprehensive comparisons from peer-reviewed sources are necessary for validation.

What are the potential implications for Monopar Therapeutics Inc. MNPR's stock performance following the late-breaker poster presentation at EASL 2025, should the data presented show significant positive outcomes?

If Monopar Therapeutics Inc. (MNPR) presents significant positive data at the EASL 2025 late-breaker session, it could lead to increased investor confidence, a surge in stock price, and heightened interest from analysts and potential collaborators in the biotech sector.

Can we expect any updates on Monopar Therapeutics Inc. MNPR's other drug candidates, such as MNPR-101-Zr, during the EASL 2025 conference or shortly thereafter?

While I cannot predict specific announcements, it's possible that Monopar Therapeutics Inc. may provide updates on MNPR-101-Zr and other drug candidates during the EASL 2025 conference or in subsequent communications, given the event’s focus on liver diseases.

**MWN-AI FAQ is based on asking OpenAI questions about Monopar Therapeutics Inc. (NASDAQ: MNPR).

Monopar Therapeutics Inc.

NASDAQ: MNPR

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