Key Inclusions
§ A detailed assessment of the overall
landscape of DNA
encoded library service providers / platform providers /
in-house companies, based on various relevant parameters, such as year of
establishment, company size (in terms of employee count), location of
headquarters, type of organization (academic / research institute,
biopharmaceutical, contract development and manufacturing organization (CDMO),
contract manufacturing organization (CMO) and contract research organization
(CRO)), library size (<1 billion, 1-10 billion and >10 billion), library
synthesis method(s) (DNA-conjugate, self-assembled, DNA-directed and
unspecified library synthesis method), library screening method(s)
(conventional screening, Artificial Intelligence (AI) / Machine Learning
(ML)-based screening and unspecified screening method), type of product(s)
offered (proprietary library, DEL synthesis package / kit and ancillary tools),
type of service(s) offered (type of library design service(s) offered - codon
(oligo) sequence design and synthesis and custom library design / synthesis,
and type of library screening service(s) offered - hit identification, hit
optimization / validation, hit to lead, sequencing, data analysis and other /
unspecified services offered), type of pharmacological lead(s) (small
molecules, macrocycles / peptides and other / unspecified molecules),
therapeutic target(s) (G protein-coupled receptors, protein-protein interactions,
enzyme targets, membrane proteins, nucleic acids, undruggable biological
targets and other / unspecified therapeutic target), therapeutic area(s)
(oncological disorders, cardiovascular disorders, neurodegenerative disorders,
inflammatory disorders, metabolic disorders, infectious diseases, ophthalmic
disorders and other / unspecified therapeutic areas) and end-user(s) (academic
/ research institute and pharma / biopharma industry).
§ A detailed analysis of various business
models adopted by the companies providing DNA encoded library platforms and
services, include operational model, service centric model and product centric
model.
§ A detailed competitiveness analysis of
DNA encoded libraries platform and service providers based on supplier strength
(in terms of year of establishment and company size) and company
competitiveness (in terms of type of business model, number of products
offered, number of services offered, number of platforms, number of
pharmacological leads, number of therapeutic area and number of therapeutic
target).
§ Elaborate profiles of the prominent
platform and service providers (shortlisted based on a proprietary criterion)
engaged in this market. Each profile features a brief overview of the company
(including information on its year of establishment, number of employees,
location of headquarters and key members of the executive team), DNA encoded
library platform and service portfolio, recent developments and an informed
future outlook.
§ A detailed analysis of the partnerships
inked between industry / non-industry stakeholders engaged in this industry,
since 2010, covering research agreements, R&D agreements, license
agreements (specific to technology platforms and product candidates), product
development agreements, product development and commercialization agreements,
mergers and acquisitions and other relevant agreements.
§ An analysis of funding and investments
that have been made into companies having proprietary DNA encoded chemical
library, including venture capital financing, capital raised from IPOs and
subsequent offerings, grants, and debt financing. It includes a detailed
analysis of the funding instances that have taken place during the period 2018
to 2023, highlighting the growing interest of venture capital (VC) community
and other strategic investors in this market.
§ An in-depth analysis of various patents
that have been filed / granted related to DNA encoded chemical library, since
2005, taking into consideration several parameters, such as publication year,
application year, patent jurisdiction, CPC symbols, leading players (in terms
of number of patents filled / granted) and type of organization. In addition,
the chapter includes a detailed patent benchmarking and an insightful patent
valuation analysis, highlighting the leading patents (in terms of number of
citations).
§ A detailed analysis of various DNA
encoded libraries focused initiatives undertaken by big pharma players
(shortlisted on the basis of the revenues generated in 2022), featuring heat
map representations that highlight the distribution of top pharmaceutical
companies and spider web representations, comparing the initiatives of big
pharma players based on multiple relevant parameters.
§ A case study on companies / organizations
that are presently engaged in supporting the development of DNA encoded
libraries. Further, chapter also includes analysis based on various relevant
parameters, such as year of establishment, company size (in terms of employee
count), location of headquarters (North America, Europe and Asia-Pacific), type
of organization (pharma / biopharma industry and academic / research
institutes) and types of support services / ancillary tools offered (building
blocks, oligos, scaffolds and other support services / ancillary tools).
§ An insightful market forecast analysis,
highlighting the future potential of the DNA encoded library market, till 2035.
We have segregated the current and upcoming opportunity based on relevant
parameters, such as application areas (hit generation / identification, hit to
lead, hit validation / optimization and other application areas), therapeutic
area (oncological disorders, immunological disorders, neurological disorders,
respiratory disorders, dermatological disorders, cardiovascular disorders,
infectious diseases and other therapeutic areas), end-users (pharma / biopharma
industry, academic / research institute and other end-users), type of payment
model employed (upfront payment and milestone payment) and key geographical
regions (North America - US, Europe - UK, Germany, Denmark, France, Switzerland
and Rest of the Europe, and Asia-Pacific - China).
The financial opportunity within the DNA encoded library market has been analyzed across the following
segments:
§ Application Area
- Hit Generation / Identification
- Hit to Lead
- Hit Validation / Optimization
§ Other Application Areas
§ Therapeutic Area
§ Oncological Disorders
§ Immunological Disorders
§ Neurological Disorders
§ Respiratory Disorders
§ Dermatological Disorders
§ Cardiovascular Disorders
§ Infectious Diseases
§ Other Therapeutic Areas
§ End-user
- Pharma / Biopharma Industry
- Academic / Research Institute
§ Other End-users
§ Type of Payment Model Employed
- Upfront Payment
- Milestone Payment
§ Key Geographical Regions
- North America
- Europe
- Asia-Pacific
The
report features inputs from eminent industry stakeholders, according to whom, DNA encoded librariesare likely to witness enhanced adoption given their advantages of optimizing
drug discovery and demonstrating greater selectivity of hit molecules for
chemical targets, thereby, offering lucrative opportunities to their
developers.
The
research also includes detailed profiles of key players (listed below) offering
DNA encoded library platforms and services; each profile features a brief
overview of the company, its financial information (if available), details on
platform and service portfolio, recent developments and an informed future
outlook.
§ AlphaMa
§ DICE Therapeutics
§ DyNAbind
§ HitGen
§ NovAliX
§ Vipergen
§ WuXi AppTec
§ X-Chem
Key Questions Answered
§ What
is a DNA encoded library?
§ What
is DNA encoded library screening?
§ How
are DNA encoded libraries made?
§ How
is information encoded in DNA?
§ How
DNA encoded libraries are revolutionizing drug discovery?
§ What
are the advantages of DNA encoded library?
§ How
many companies are developing DNA encoded libraries?
§ Which
type of business model is widely adopted by companies in DNA encoded library
market?
§ What
is the current landscape of patents filed for DNA encoded libraries?
§ Who
are the key players in the DNA encoded library market?
§ What
are the leading market segments in the global DNA encoded library market?
§ Which
region captures the largest share in the DNA encoded library market?
§ What
is the likely growth rate (CAGR) for DNA encoded library market?
To
view more details on this report, click on the link:
https://www.rootsanalysis.com/reports/view_document/dna-encoded-libraries/288.html
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